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    Retino-A contains the active ingredient Tretinoin, a carboxylic acid form of vitamin A, is a first generation topical retinoid. It is commonly used to treat acne and keratosis pilarisis (a harmless skin condition that causes rough, dry patches and tiny bumps, usually on the cheeks, upper arms, buttocks, and thighs). Tretinoin is on the WHO list of essential medicines, a list of the most important medicines required in a basic health system. Retino-A is indicated for topical use in the treatment of acne vulgaris, in which blackheads, papules, and pustules predominate. It is not recommended as monotherapy in case of acne conglobata (a highly inflammatory disease with blackheads, nodules, pustules, and draining sinus tracts). The drug being a metabolite of retinol, is both structurally and pharmacologically related to vitamin A, which regulates the cell growth and regenerates the outer layer of the skin. It makes the surface layer of the skin thinner and pores less likely to become blocked, reducing the occurrence of blackheads, whiteheads, and pimples. Concomitant topical medication, abrasive soaps and cleansers, cosmetics that have a strong drying effect, and products with high concentration of astringents, alcohol, spices or lime should be used with caution because of the possible drug interaction with Retino-A. It may decrease the number and severity of acne pimples and promote quick healing of pimples that do develop. Tretinoin belongs to a class of medications called retinoids. Read the Patient Information Leaflet if one is available from your pharmacist. Consult your doctor or pharmacist if you have questions. Gently clean the affected skin with a mild or soapless cleanser and pat dry. Use your fingertips to apply a small amount of medication (about the size of a pea) in a thin layer, usually once daily at bedtime or as directed by your doctor. A gauze pad or cotton swab can be used to apply the liquid. For some preparations, you should wait 20-30 minutes after cleaning your face before applying this medication. Consult the label directions, the Patient Information Leaflet, or your pharmacist if you have any questions. Do not apply to the inner lip area or inside the nose/mouth.

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