Voltaren Gel (diclofenac) was the first prescription topical treatment for osteoarthritis approved by the Food and Drug Administration (FDA). Voltaren Gel, a nonsteroidal anti-inflammatory drug (NSAID) in topical form, is mostly used on knees and hands. If you're thinking about taking Voltaren Gel, here's what you need to know about the drug's safe use and effectiveness. The systemic absorption of Voltaren Gel, which is 1 percent diclofenac sodium in a topical gel formulation, is 94 percent less than oral diclofenac. That means the risk of serious gastrointestinal and cardiovascular side effects associated with oral NSAIDs is considerably less with the topical formulation. The FDA approval was based on several studies, including two randomized, double-blind, placebo-controlled efficacy studies and a 12-month safety study. After six weeks of treatment in an efficacy study of people with hand osteoarthritis, pain levels were reduced by 46 percent. Diclofenac Sodium Gel, 3%, contains the active ingredient, diclofenac sodium, in a clear, transparent, colorless to slightly yellow gel base. Diclofenac sodium is a white to slightly yellow crystalline powder. It is freely soluble in methanol, soluble in ethanol, sparingly soluble in water, slightly soluble in acetone, and partially insoluble in ether. The chemical name for diclofenac sodium is: Sodium [o-(2,6-dichloranilino) phenyl] acetate Diclofenac sodium has a molecular weight of 318.13. The structural formula is represented below: Diclofenac Sodium Gel, 3% also contains benzyl alcohol, hydroxyethyl cellulose, methoxypolyethylene glycol 350, PEG-60 hydrogenated castor oil, and purified water. 1 g of Diclofenac Sodium Gel, 3% contains 30 mg of the active substance, diclofenac sodium. The mechanism of action of diclofenac sodium in the treatment of actinic keratoses (AK) is unknown. The contribution to efficacy of individual components of the vehicle has not been established. Zithromax gonorrhea Cialis risks Antabuse price Canadian pharmacies online Diclofenac Sodium Gel, 3%, contains the active ingredient, diclofenac sodium, in a clear, transparent, colorless to slightly yellow gel base. Diclofenac sodium is. Find patient medical information for Diclofenac Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Jul 12, 2017. A label for Diclofenac Sodium extended-release tablets. Credit NIH. Diclofenac is a pain reliever in the drug class NSAID non-steroidal. Diclofenac is a medicine called a non-steroidal anti-inflammatory drug. Before you take diclofenac, let your doctor know if you have ever had a bad reaction to any other anti-inflammatory painkiller. Make sure you take the tablets/capsules as directed on the label of the pack. Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with diclofenac. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome. Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. Diclofenac works by blocking the effect of chemicals in your body, called cyclo-oxygenase (COX) enzymes. Diclofenac Sodium 75 MG Injection is a Non-steroidal anti-inflammatory (NSAID) drug used to treat pain associated with conditions like Gout, Migraine, Rheumatoid Arthritis, sprains of muscles and joints and in mild to moderate fever in some cases. The effect of this medicine can be observed within 10-30 minutes of consumption. Note: Potassium salts of Diclofenac act faster than the Sodium salts as they are absorbed faster from the Gastro-Intestinal Tract. Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of serious side effects such as severe gastrointestinal bleeding, dizziness, fatigue, weakness, etc. Oral, topical and rectal forms: Use Diclofenac Sodium 75 MG Injection as advised by your doctor. You may take the oral form of this medicine with or after food. Do not use in larger or smaller amounts than advised. Diflucan sodium Diflucan - Uses, Side Effects, Interactions -, Diclofenac Sodium - WebMD Viagra versus cialis which is betterAmoxicillin alcohol Jul 15, 2018. Diclofenac Topical osteoarthritis pain learn about side effects, dosage, special precautions, and more on MedlinePlus. Diclofenac Topical osteoarthritis pain MedlinePlus Drug Information. What is Diclofenac Voltaren? - Live Science. Common Side Effects of Voltaren Diclofenac Sodium Drug Center.. Anhydrous silica, magnesium stearate, sodium lauryl sulfate, titanium dioxide. The dose of DIFLUCAN may need to be reduced in patients with impaired renal. Find patient medical information for Diclofenac Sodium Topical on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user. Diclofenac topical gel is a prescription medication that's used to treat osteoarthritis pain in certain joints. It's also used to treat actinic keratoses. This medication.